歯科薬物療法
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
酢酸ミデカマイシンの口腔感染症に対する臨床効果
押尾 武松原 完也加藤 隆三玉井 健三北 進一鈴木 貢吉沢 信夫埜口 五十雄根本 一男大西 正俊小谷 朗茂木 克俊古田 勲石井 保雄佐藤 匠島田 桂吉堀 亘孝杉村 正仁坂本 忠幸浜田 驍尾崎 登喜雄長畠 駿一郎芝 良祐清水 正嗣山城 正宏
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1986 年 5 巻 2 号 p. 67-77

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The results of clinical studies on MOM for oral use, performed at 22 institutes in this country, are summarized in this protocol. The conclusions obtained is as follows:
1) Clinical efficacy of MOM oral administration was evaluated in 113 patients with oral infectious disease, and 82.3% responded to the drug.
2) Clinical efficacy of MOM at a daily dose of 600 mg was 83.2% based on committee-judgement and 80.0% based on doctors' judgement.
3) MOM shows antibacterial activity against aerobes, anaerobes and mixed infection cases.
4) In 4 of the 160 cases treated, gastrointestinal symptoms were appeared.
5) From the above results, it was concluded that MOM was a useful new antibiotic for the treatment of oral infections.
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