巻号一覧
5 巻 (1986)
- 3 号 p. 121-
- 2 号 p. 47-
- 1 号 p. 1-
5 巻, 2 号
選択された号の論文の10件中1～10を表示しています
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大杉 惠子, 岩佐 俊明, 宮内 重幸, 堀越 勝, 名倉 英明, 榎本 昭二1986 年 5 巻 2 号 p. 47-54
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーCefotetan, a long-acting cephalosporin, was administered to 29 cases to prevent postoperative infection in lesions of oral surgery. The patients were given the antibiotics just before or after the operation, and then they were given for 4 to 15 days daily. The patients were divided into 2 groups. Group A was administered once a day, and group B was administered twice a day. The following results were obtained from the fundamental and clinical studies.
1) Clinically, no postoperative infection was seen in any of the cases, and there were no significant differences in the clinical courses of wound healing between group A and B.
2) One patient got fever and skin rashes, which were thought to be side effects of CTT.
3) Serum and tissue concentration were measured in 6 cases. This revealed dose response to a high concentration over a long period.
4) Summarizing the above results, CTT was considered to be effective and safe for preventing postoperative infection in lesions of oral surgery, and we could say administering CTT once a day was as effective as twice a day.抄録全体を表示PDF形式でダウンロード (747K) -
加藤 隆三, 松原 完也, 押尾 武, 玉井 健三, 北 進一, 鈴木 貢, 吉沢 信夫, 埜口 五十雄, 根本 一男, 大西 正俊, 小谷 ...1986 年 5 巻 2 号 p. 55-66
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーStudies on the bacteriological movements after administration of Midecamycin acetate (MOM) on the oral infections were performed by 23 institutes in this country, and the following results were obtained:
Of the 86 cases of infections in the oral cavity which were examined, 3/4 of them were suppurative infections and had rather good antibacterial activity against gram-positive bacteria and Bacteroides species. We used 238 strains of isolated organisms from clinical materials in our laboratory during June and October, 1985. We examined the antibacterial activity of MOM against 238 strains. MOM has quite good antibacterial activity against isolated anaerobes.抄録全体を表示PDF形式でダウンロード (1184K) -
押尾 武, 松原 完也, 加藤 隆三, 玉井 健三, 北 進一, 鈴木 貢, 吉沢 信夫, 埜口 五十雄, 根本 一男, 大西 正俊, 小谷 ...1986 年 5 巻 2 号 p. 67-77
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーThe results of clinical studies on MOM for oral use, performed at 22 institutes in this country, are summarized in this protocol. The conclusions obtained is as follows:
1) Clinical efficacy of MOM oral administration was evaluated in 113 patients with oral infectious disease, and 82.3% responded to the drug.
2) Clinical efficacy of MOM at a daily dose of 600 mg was 83.2% based on committee-judgement and 80.0% based on doctors' judgement.
3) MOM shows antibacterial activity against aerobes, anaerobes and mixed infection cases.
4) In 4 of the 160 cases treated, gastrointestinal symptoms were appeared.
5) From the above results, it was concluded that MOM was a useful new antibiotic for the treatment of oral infections.抄録全体を表示PDF形式でダウンロード (1011K) -
佐々木 次郎, 森鼻 健史, 植松 正孝, 高井 宏, 池嶋 一兆, 椎木 一雄, 橋本 哲朗, 河西 一秀, 三宮 慶邦, 桑沢 隆補, ...1986 年 5 巻 2 号 p. 78-86
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーOfloxacin (OFLX), a new oral quinolone antibacterial agent, was evaluated on clinical efficacy and safety in the field of oral and maxillofacial surgery. OFLX was administered at a dose of 200 mg t.i.d. to 159 patients and 153 patients were adopted for clinical evaluation. These patients consisted of 80 with periodontal infections, 23 with pericoronitis and 50 with osteitis of the jaws. The following results were obtained:
1) The clinical efficacy rate was 83.7% according to judgement by the doctors in charge and 82.8% according to judgement by numerical rating on the 3rd day.
2) One hundred and eighty four strains of bacteria were isolated from 83 patients. The isolation rate of aerobic bacteria was 40.8% and that of anaerobic bacteria was 59.2%. Bacteriological response was eradication in 68, persistence in 4 and unknown in 11.
3) Adverse reactions were observed in 5 patients (3.2%), but symptoms were not serious and soon disappeared. Abnormal changes in laboratory findings were found in 4 patients but they were not serious.抄録全体を表示PDF形式でダウンロード (1003K) -
佐々木 次郎, 森鼻 健史, 植松 正孝, 高井 宏, 池嶋 一兆, 椎木 一雄, 橋本 哲朗, 河西 一秀, 三宮 慶邦, 桑沢 隆補, ...1986 年 5 巻 2 号 p. 87-96
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーBacteriological studies were carried out in the field of oral and maxillofacial surgery. One hundred and ninety eight strains were isolated from the pus of closed abscesses in 88 patients with odontogenic infections. Their susceptibilities to Ofloxacin (OFLX), Ciprofloxacin (CPFX), Ampicillin (ABPC), Erythromycin (EM) and Cephalexin (CEX) weredetermined. The results obtained were as follows:
1) Peptostreptococcus spp., α-Streptococcus and anaerobic streptococci were isolated in high frequency and these 3 strains occupied 67.7% of all the strains.
2) The isolated percentage of aerobes and anaerobes was 42.4% and 57.6%, respectively, and anaerobes were isolated from 78 out of 88 patients. These results suggest the important role of anaerobes in odontogenic infections.
3) As a whole, ABPC exhibited strong antibacterial activities. OFLX and CPFX inhibited the growth of almost all the strains at a concentration of less than 6.25μg/ml. Though EM showed good antibacterial activity, some highly resistant Peptostreptococcus spp. and anaerobic streptococci were isolated. CEX had lower activity compared with the other 4 drugs.抄録全体を表示PDF形式でダウンロード (827K) -
藤井 彰, 久保山 昇, 田村 豊幸1986 年 5 巻 2 号 p. 97-100
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーThe effect of amfenac sodium (Fenazox®) on experimentally induced toothache was investigated by applying reflex jaw opening introduced by electrical stimulation of the exposed tooth nerve of the lower canine. Mefenamic acid 30 mg/kg and dichlofenac sodium 5 mg/kg were used as the positive controls. The following results were obtained:
1) Amfenac sodium 1 mg/kg gave approximately the same analgesic effect as mefenamic acid 30 mg/kg. Dichlofenac sodium 5 mg/kg gave a better analgesic effect than either amfenac sodium 1 mg/kg or mefenamic acid 30 mg/kg.
2) Amfenac sodium 5 mg/kg gave the strongest analgesic effect among the drugs tested. A stronger analgesic effect than the maximum effects of dichlorofenac sodium 5 mg/kg and mefenamic acid 30 mg/kg was found 1.5 to 4 h after the administration of the drugs.
These results indicate that amfenac sodium might be an effective analgesic for the treatment of toothache.抄録全体を表示PDF形式でダウンロード (1729K) -
辻 恵一, 堀越 勝, 斉藤 道雄, 松本 堅太郎, 朝比奈 泉, 谷 政澄, 榎本 昭二1986 年 5 巻 2 号 p. 101-104
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーThe evaluation of a new enteral nutritional product, Clinimeal®, in the field of oral surgery was compared with that of the hospital diet which was minced by mixer. Clinimeal was tolerated up to a maximum dose of 1, 850-1, 950 kcal/day. In the group which was administered Clinimeal by tube feeding, the concentration of prealbumin and transferrin in the blood plasma showed a tendency to increase. As a side effect of the Clinimeal, occasional diarrhea was observed, however severe diarrhea was observed in only 4 of 30 patients (13%) . This percentage was somewhat smaller than that of the minced diet. Clinimeal had the advantage of easy pumping. The usefulness of Clinimeal may be improved by making it in a variety of flavors.抄録全体を表示PDF形式でダウンロード (452K) -
影向 範昭1986 年 5 巻 2 号 p. 105-108
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーThe amount adsorbed and the mode of adsorption onto cellulose products of benzalkonium chloride (BC) were determined in an effort to estimate a possible reduction by adsorption of the concentration of this disinfectant in solutions in actual use.
BC in aqueous solution was quickly adsorbed onto cellulose products, a quasi-equilibrium being attained in a matter of 10 minutes of contact.
Under these conditions the adsorption of BC was shown to take place according to the Langmuir's adsorption isothermal line. The maximum quantity of BC adsorbed as estimated from the Langmuir's formula was 6.4 mg/g of absorbent cotton, 4.5 mg/g of cotton balls and 3.1 mg/g of gauze.
When 5 g of cellulose products are immersed in 100 ml of 0.025% BC solution, the final concentration of BC as calculated from the Langmuir's formula is reduced to 0.0073% with absorbent cotton, 0.0133% with cotton balls, and 0.0188% with gauze. In order to secure a final BC concentration of 0.01%, respective initial BC concentrations of 0.030%, 0.020% and 0.014% are required for absorbent cotton, cotton balls and gauze. By the same token, in order to secure a final BC concentration of 0.025%, respective initial BC concentrations of 0.051%, 0.040% and 0.032% are required.
These results clearly indicate that BC, having a remarkable liability to be adsorbed onto cellulose products, it is necessary to pay due regard to this property of the disinfectant in determining its concentration in the solution to be used.抄録全体を表示PDF形式でダウンロード (403K) -
向井 洋, 山下 佐英1986 年 5 巻 2 号 p. 109-113
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーDuring the past 3 years, 21 patients with squamous cell carcinoma of the oral region were treated with so-called BM therapy (the continuous combination therapy of Peplomycin and Mitomycin C) . Thirteen cases were male, and 8 were female. The ages ranged from 28 to 78 years with a mean age of 56.3 years. As to the primary sites, 7 cases were in the mandibular gingiva, 6 in the floor of the mouth, 5 in the tongue, 2 in the maxillary gingiva and 1 in the buccal mucosa.
One to three courses of BM therapy were carried out. The overall response rate was 22.2% with 4 cases having partial response (≥50% regression) . Histological grading on the primary tumor by Shimosato et al, was from Grade I to III.
Side effects were detected in 13 cases (61.9%), in 2 of which BM therapy was discontinued.抄録全体を表示PDF形式でダウンロード (510K) -
松井 義郎, 吉田 広, 杉本 明, 舘野 孝行, 登倉 博子, 道脇 幸博, 大澤 毅晃, 道 健一1986 年 5 巻 2 号 p. 114-120
発行日: 1986/08/31
公開日: 2010/06/08
ジャーナル フリーA case of a parapharyngeal space abscess secondary to submandibular cellulitis of the contralateral side is presented.
The patient is a thirty-year old male. He was referred to our hospital complaining of pain and swelling of the right submandibular region. After three days, swelling of the left cheek and hoarseness was noted.
According to the clinical symptoms and CT findings, it was diagnosed as a left parapharyngeal space abscess. He was treated successfully by an incision for the abscess of the parapharyngeal space and administration of antibiotics. In this case, it is suspected that the infection may have spread to the contralateral side parapharyngeal space through the pathway of the connecting fascial space.抄録全体を表示PDF形式でダウンロード (3308K)
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