Abstract
The non-steroidal anti-inflammatory agent, Amfenac sodium (Fenazox®, 1 capsule 50 mg) was administered to 118 cases at pain time after exodontias and minor operations at our clinic between December, 1986 and May, 1987.
Out of 118 cases, 61 were able to be evaluated. We classified the 61 cases into 4 groups, i.e. Group 1; usual exodontias, Group 2 ; surgical exodontias (underwent bone cutting), Group 3 ; operations on soft tissue, Group 4 ; operation on hard tissue.
The analgesic effects were evaluated with estimation by the patients using selt-checking cards and by the doctors. The following results were obtained :
1) In 43 cases (70%), analgesic effects appeared within 30 min after receiving 1 capsule of Amfenac sodium, and in 58 cases (95%) within 1 h.
2) Transition of the degree of pain for each group are displayed in Figs. 2-5. These figures show that the analgesic effect appeared about 30 min after administration and lasted for 3-4h.
3) Total effects were classified into 4 grades, “excellent” in 38 cases (62%), “effective” in 12 cases (20%), “slightly effective” in 10 cases (16%), and “non-effective” in 1 case (2%) .
4) Side effects were recorded in 4 cases (7%), but they were mild and disappeared soon without any treatment.
5) Total usefulness was classified into 5 grades, “highly useful” in 36 cases (59%), “useful” in 13 cases (21%), “slightly useful” in 11 cases (18%), “not useful” in 1 case (2%), and “worse” in no cases.
According to the results, the non-steroidal anti-inflammatory agent, Amfenac sodium (Fenazox®) was effective for pain after exodontias and minor operations and was also safe and useful. It is worth noting that the analgesic effect appeared rapidly.
