Usefulness of the prick-prick test for diagnosis of food-dependent exercise-induced anaphylaxis caused by yellow peach

Abstract

We experienced a case of food-dependent exercise-induced anaphylaxis (FDEIA) caused by ingestion of canned yellow peach. The result of Immuno CAP^® (CAP) for peach was negative, and there was no scratch extract for peach. Therefore, the prick-prick test was performed using canned yellow peach; it gave a positive result. The selection of food items is very important in provocation tests because the positive rate of provocation test for FDEIA is low. We retrospectively analyzed reports of Japanese patients with FDEIA, except wheat-dependent exercise-induced anaphylaxis, published in medical journals from 1983 to 2009. The positive rate of the prick-prick test performed alone was lower than that of the skin prick test and CAP. However, the combination of the prick-prick test and CAP increased the number of cases with positive results and was useful in determining food items for provocation tests.