Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
Online ISSN : 1882-2738
Print ISSN : 0914-2649
ISSN-L : 0914-2649
A case of food protein-induced enterocolitis syndrome triggered by rice that developed tolerance over time
Naoko SuzukiYukihiko KawasakiHisao OkabeFumi MashiyamaHiroko Sakuma
Author information
JOURNAL RESTRICTED ACCESS

2025 Volume 39 Issue 2 Pages 131-136

Details
Abstract

In recent years, there have been some reports of food protein-induced enterocolitis syndrome (FPIES) triggered by rice. However, there are few reports on nutritional management following the elimination of rice in cases of rice-induced FPIES. Herein, we report on our experience a 6-month-old girl who was diagnosed with FPIES due to rice. She began to vomit repeatedly 30 minutes after consuming rice porridge for the first time. Based on the appearance of symptoms after rice intake, negativity for rice-specific IgE antibodies, negative skin test results, and positive food oral challenge test results, she was diagnosed with FPIES due to rice. As treatment, rice consumption was completely eliminated, and her growth and development were observed while providing nutritional guidance. We managed nutrition by using wheat products as the staple food, changing the form of wheat intake and eventually using oatmeal. At 2 years and 4 months of age, an oral rice challenge test produced negative results and, thereafter, she increased her rice intake at home, eventually developing tolerance to rice at 2 years and 8 months of age. Although FPIES triggered by rice is a rare disease, this disease should be considered as one of the differential diagnoses in cases of repeated vomiting of unknown cause.

Content from these authors
© 2025 Japanese Society of Pediatric Allergy and Clinical Immunology
Previous article Next article
feedback
Top