生薬学雑誌
Online ISSN : 2433-8486
Print ISSN : 1349-9114
天然薬物ノート
Chemical Constituents in the Whole-plant Extract of Agrimonia eupatoria and Their Aldose Reductase Inhibitory Activities
Tomoki IguchiMinpei KurodaChihiro KanTakuya FujiiYoshihiro Mimaki
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2020 年 74 巻 1 号 p. 60-61

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A previously undescribed compound 1, along with (+)-catechin (2), (-)-epicatechin (3), five known flavonol derivatives (48), and an agrimonolide derivative (9) were isolated from the MeOH extract of the whole plants of Agrimonia eupatoria. Compounds 1 and 48 exhibited aldose reductase inhibitory activity with IC50 values between 15.6 and 21.9 μM.

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© 2020 The Japanese Society of Pharmacognosy
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