Identification of Flavone C-glycosides from Glycyrrhiza uralensis Seeds and Their Effects on AMPK Activation

Yukiko Matsuo; Tomoki Iguchi; Minpei Kuroda; Mizue Ishiguro; Takuro Nara; Kazuhiro Takatori; Yoshihiro Mimaki

doi:10.24684/jspharm.74.2_108

天然薬物ノート

Identification of Flavone C-glycosides from Glycyrrhiza uralensis Seeds and Their Effects on AMPK Activation

Yukiko Matsuo, Tomoki Iguchi, Minpei Kuroda, Mizue Ishiguro, Takuro Nara, Kazuhiro Takatori, Yoshihiro Mimaki

著者情報

キーワード: Glycyrrhiza uralensis, Leguminosae, Seed, Isoschaftoside, Flavone C-glycoside, AMPK

ジャーナルフリー

2020 年 74 巻 2 号 p. 108-109

DOI https://doi.org/10.24684/jspharm.74.2_108

詳細

抄録

Seven flavone C-glycosides (1－7) were isolated from the seeds of Glycyrrhiza uralensis for the first time. The structures of 1－7 were primarily identified using NMR spectral data analysis. Isoschaftoside (3) significantly activated AMPK expression in HepG2 human hepatoma cells compared to the control.

責任著者(Corresponding author)

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