2025 Volume 42 Issue 2 Pages 146-149
We report a case of Mpox virus infection in 30s-year-old man. He had sexual contact with a multiple sex partner one month ago. He had a fever and skin rash (erythema, papules or pseudopustules) on his chest, forearms, palms, and penis. Microscopic examination of the skin biopsied specimen from his chest revealed epidermal necrosis with shadow cells, balloon cell degeneration, and exocytosis of neutrophils. Eosinophilic inclusion bodies were observed in keratinocytes. A final diagnosis of Mpox virus infection was confirmed by PCR. As the histopathological features are not specific for Mpox virus infection, it is necessary to interactively diagnose in combination with patient’s history and clinical findings.