A case of mixed neuroendocrine-non-neuroendocrine neoplasm （MiNEN）with squamoid morule of the colon

Abstract

We report a case of mixed neuroendocrine-non-neuroendocrine neoplasm （MiNEN） with squamoid morule.　A 44-year-old man presented with fresh blood hemorrhage in his stool.　Endoscopic examination revealed a colon tumor and the patient subsequently underwent right hemicolectomy.　Histologically, the tumor contained both adenocarcinoma and neuroendocrine tumor （NET G3） components with each component occupying more than 30% of the tumor.　Both components exhibited squamoid morule.　The patient was diagnosed with MiNEN with squamoid morule, which are rare.