Journal of Japanese Society of Psychosomatic Obstetrics and Gynecology
Online ISSN : 2189-7980
Print ISSN : 1345-2894
ISSN-L : 1345-2894
The effect of food product including Bovine AlphaS1-Casein Tryptic Hydrolysate and Theanine on sleep in postmenopausal women with complaint of deteriorated sleep health
Noriko MatsuuraNaomi AdachiShunjiro KobayashiTaku NakanoShuichiro Shirakawa
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2016 Volume 21 Issue 1 Pages 114-120


We examined the effects of food product including bovine alphas1-casein tryptic hydroly-sate (casein peptide) +L-theanine and a placebo on subjective sleep quality in middle-aged women with complain of deteriorated sleep health. The study was designed as a cross over double blind study. Each participant ingested casein peptide+L-theanine or placebo at 1 hour before bedtime for consecutive ten days and with a 4-day washout period between ingestions. The participants evaluated their sleepiness, mood, sleep quality questionnaires during the last three days of ingestion period. Pittsburg Sleep Quality Index and climacteric symptom questionnaire were completed at the end of periods. Through the analysis of 11 females aged 56 to 69 years, casein peptide+L-theanine significantly increased sleepiness score measured on a visual analog scale at bedtime and total score of the Pitts- burg Sleep Quality Index compared to placebo. In comparison with the prior survey conducted before ingestions, score of autonomic nervous symptoms in the Simplified Menopausal Index significantly improved with casein peptide+L-theanine. Thus, casein peptide+L-theanine increased sleepiness before bedtime and improve the quality of sleep. The combination effect may beneficial for promoting sleep health of middle-aged woman.

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© 2016 Japanese Soiety of Psychosomatic Obstetrics and Gynecology
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