PMS (Premenstrual syndrome) is an uncomfortable condition characterized with various kinds of affective and somatic symptoms which often occur reproducibly during the luteal phase of the menstrual cycle. Its clinical diagnosis is based on the prospective daily recording of menstruation-associated symptoms. We developed a novel system of symptom-recording by a smartphone application (app) which collects and saves the data concerning the women's daily health condition. As a feasibility study, the 28 participants were randomly divided into 2 groups and they challenged recording for 84 days ; using the smartphone app (in the ‘app' group) or handwriting on pape (r in the ‘paper' group) . There was no significant difference in the number of days on which they exerted recording. Surveying their impressions by a questionnaire, we found the tendency that feeling of being connected with the clinician was stronger in the app group and that introspection and self-care were more encouraged in the paper group. The recording in the smartphone app induced no adverse events and was shown to promote the doctor-patient communication. Since the daily recording itself has preferable effects on PMS, the ICT systems may be utilized effectively and widely in the general public in order to improve women's healthcare.
We examined the effects of food product including bovine alphas1-casein tryptic hydroly-sate (casein peptide) +L-theanine and a placebo on subjective sleep quality in middle-aged women with complain of deteriorated sleep health. The study was designed as a cross over double blind study. Each participant ingested casein peptide+L-theanine or placebo at 1 hour before bedtime for consecutive ten days and with a 4-day washout period between ingestions. The participants evaluated their sleepiness, mood, sleep quality questionnaires during the last three days of ingestion period. Pittsburg Sleep Quality Index and climacteric symptom questionnaire were completed at the end of periods. Through the analysis of 11 females aged 56 to 69 years, casein peptide+L-theanine significantly increased sleepiness score measured on a visual analog scale at bedtime and total score of the Pitts- burg Sleep Quality Index compared to placebo. In comparison with the prior survey conducted before ingestions, score of autonomic nervous symptoms in the Simplified Menopausal Index significantly improved with casein peptide+L-theanine. Thus, casein peptide+L-theanine increased sleepiness before bedtime and improve the quality of sleep. The combination effect may beneficial for promoting sleep health of middle-aged woman.