Abstract
Patient 1 was 30 years old female. She suffered from Graves' disease in spite of antithyroid drug treatment for 2.5 years and combined depressive state. In consequence of the treatment with supportive psychotherapy together with antithyroid drug, she has become aware of her over adaptation in personal relation and changed to be able to express her emotion properly. At last she has got both remission of hyperthyroidism and depressive state. Then she has hardly become to suffer from common cold. Patient 2 was 15 years old female, whose body weight becomes from 56kg to 38kg by a loss in weight. She has also suffered from binge eating, vomiting and amenorrhea. As a result of examination, she has been diagnosed to be a combination of Graves' disease and eating disorder. Because she could not continue antithyroid drug treatment due to phobia to weight gain, therapeutic plan has been reevaluated with her mother and she has consent subtotal thyroidectomy at last. Now she is maintaining body weight of about 40kg and stable mental state though she is replaced thyroid hormone. In conclusion, psychosomatic approach contributes to improve not only hyperthyroidism but also stress related complications in female Graves' disease patients.
