Abstract
We report updates of our coexpression database, ATTED-II (http://atted.jp), focusing on two new features: condition-specific coexpression and homologous coexpression with rice. For analyses of a broad range of biological phenomena, it is important to collect data under diverse experimental conditions, but the meaning of coexpression can become ambiguous under these conditions. One approach to overcome this difficulty is to calculate the coexpression for each set of conditions with a clear biological meaning. With this viewpoint, we prepared five sets of experimental conditions (tissue, abiotic stress, biotic stress, hormones and light conditions), and users can evaluate the coexpression by using comparative gene lists and switchable gene networks. We also added rice coexpression data to compare Arabidopsis coexpression data. Comparison of Arabidopsis and rice coexpression data will make it possible to investigate conservation of coexpression among flowering plants. With the ability to investigate condition-specific coexpression and species conservation, ATTED-II can help researchers to clarify the functional and regulatory networks of genes in a broad array of plant species.
