2016 年 4 巻 1 号 p. 24-29
Aim: Oligohydramnios contributes to a negative fetal prognosis. Management of oligohydramnios in obstetric clinical practice is important. We assessed the clinical efficacy of Gorei-San for the treatment of oligohydramnios.
Methods: Single deepest pocket (SDP) changes before and after treatment for oligohydramnios (SDP decrease to less than 3 cm) were examined. A total of 51 pregnant mothers who were experiencing oligohydramnios were enrolled in the study. The changes in SDP were compared between 27 women treated with Gorei-San (7.5 g/day) and 24 untreated women. The first measurements of SDP in both groups were obtained when the SDP had decreased to less than 3 cm (start point: SP), and the second measurements were obtained at the next regular examination (end point: EP).
Results: The average SDP significantly increased in women treated with Gorei-San from the SP (2.37±0.41 cm) (mean±SD) to the EP (3.15±0.62 cm) (mean±SD) (P<0.001). In contrast, there were no significant changes in the untreated women from the SP (2.5±0.15 cm) (median±quartile) (non-normally distributed) to the EP (2.63±0.68 cm) (mean±SD) (P=0.59).
Conclusions: Gorei-San was helpful in the treatment of oligohydramnios. Although further studies are needed to confirm our findings, we believe that this new application of Gorei-San for the treatment of oligohydramnios is a clinically applicable strategy.
