質量分析顕微鏡のバイオナノテクノロジーへの応用

抄録

We invented a MS microscope for anatomists or cell biologists, because we wish to know what we see. Mass spectrometry has played an important role in the proteomics research in the post-genomic era. Proteomics data obtained by mass spectrometry are now being combined with spatial information, which is called mass imaging. The current mass imaging techniques, however, do not provide molecular identifications. Our instrument, an MS microscope, will provide observation and identification using a tandem mass spectrometer equipped with a new concept mass analyzers. We believe that this instrument will contribute to both biological and medical applications.