2014 年 35 巻 1 号 p. 30-33
Evaluation of the adhesion properties of dermal and transdermal patches (i.e. poultice and tape) applied to the skin is very important. Several physical test methods are used as quality tests of patch adhesion. However, it has been well-known that physical test and human sensory may not correlate well, particularly in case of poultice. We have developed a novel tack method using the phosphor-bronze thin plate and have evaluated adhesiveness of poultice and compared human sensory results. Additionally, cohesiveness of poultice has also evaluated using the filter paper. These methods are thought to evaluate the adhesive properties of patch products and also apply for the evaluation of novel formulation development.