VIRUS
Online ISSN : 1884-3425
ISSN-L : 1884-3425
インフルエンザワクチンの力價檢定法の研究
西川 文雄加地 正郎福見 秀雄
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ジャーナル フリー

1953 年 3 巻 2 号 p. 121-127

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Neutralization reaction for the potency measurement of the influenza vaccine has so far been carried out by means of mouse inoculation procedure, but this involves some disadvantages, namely first, sometimes non-specific lesions are encountered with in the lungs of mice autopsied and disturbs correct judgement of infective endopoint, second, if newly isolated virus strains would be employed for production and consequently potency measurement of vaccine, it might be difficult to use mice for potency measurement because most of newly isolated strains of influenza virus require more or less time to be adapted to mice, and so on. In these reason experiments were made to obtaine some data necessary for carrying out potency measurement of vaccine with eggs. (Refer to Pp. 123-125)
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© 日本ウイルス学会
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