ウイルス
Online ISSN : 1884-3433
Print ISSN : 0042-6857
ISSN-L : 0042-6857
溶原化の機転に関する研究
第2報 溶原化決定におけるChloramphenicolの効果
遠藤 啓三
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ジャーナル フリー

1960 年 10 巻 4 号 p. 240-245

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抄録
It has been found that the chloramphenicol is a drug to inhibit protein synthesis selectively. The effect of this drug on various response types of infected bacteria was examined. As a result, it was proved that lysogenic response was largely increased after the exposure for a certain period while lytic response was inhibited strikingly.
Attempt was made to determine at what stage of eclipse addition of this drug was effective to shift to lysogenic response. Consequently, it was shown to be able to intensify the proportion of lysogenic response by the time a little before the end of eclipse period.
The author concluded that the decision of lysogenic response was possible throughout the period of vegetative growth, and that from the standpoint of the kinetics of lysogenization two mechanisms, i.e., decision and establishment, should be regarded separately.
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