Abstract
The present paper concerns the alteration of nitrogen metabolism of TMV-infected tobacco leaf discs induced by some antiviral substances using detached leaf tissue-culture procedure. The amount of soluble protein nitrogen in infected leaves decreased in the early stage of infection, and later increased with a stage of corresponding decrease of the amount of non-protein nitrogen and of increase of virus titer. 2-Thiouracil and mitomycin C-treatments altered this trend to the levels of uninfected tissues and a significant accumulation of insoluble protein component was observed. The inhibitory action of naramycin was different from this, and an increase in the amount of non-protein nitrogen and a decrease in that of insoluble protein nitrogen were characteristic.
