抄録
Lipovirus is a new transmissible cytopathic agent, possibly isolated from the acute phase blood of an infectious hepatitis patient.
The optimal temperature for the development of specific degeneration in lipovirus-infected culture was 33°C. Partial and complete suppression was noted at 37°C and 38°C respectively. The lipovirus was lethal to chick embryos if the virus was inoculated into the amniotic or allantoic sacs or onto the chorioallantoic membrane and the embryos then incubated at 33°C. Inoculation into the yolk sac or elevation of incubation temperature to 38°C nullified the lethal action of the lipovirus on chick embryos. A little lipovirus replicated in the spleen and liver of artificial induced hypothermic mouse.
Consequently, the replication of the lipovirus in vitro, in ovo and in vivo was powerfully accelerated at 33°C, relatively low temperature and temperature elevation generally resulted in the suppression of virus multiplication.
