ウイルス
Online ISSN : 1884-3433
Print ISSN : 0042-6857
ISSN-L : 0042-6857
Myxovirus Pyrogenに関する研究 III
Influenza virusおよび細菌性発熱物質により産生される白血球性発熱物質の異同について
川崎 浩之進加納 晴三郎
著者情報
ジャーナル フリー

1974 年 24 巻 1 号 p. 51-56

詳細
抄録

Studies were made on the physico-chemical properties of leucocytic pyrogens induced by influenza virus (V) and bacterial pyrogen of Escherichia coli (LPS) in rabbits. The following results were obtained.
1. The fever curve of the virus (256HAU/kg, i.v.) was quite different in lag time from that of LPS (0.1μg/kg, i.v.). The fever curves of the leucocytic pyrogens were quite similar to each other.
2. The chromatographic patterns over Sephadex (G-200) or Bio gel (P-150) of the two leucocytic pyrogens were shown to be the same as that of control leucocytic pyrogen.
3. The immuno-diffusion patterns of both leucocytic pyrogens against antiserum of guinea pig were the same, showing two or three precipitating bands.
From the results mentioned above, it was concluted that both pyrogens (V and LPS) might be mediated by the same leucocytic pyrogens.

著者関連情報
© 日本ウイルス学会
前の記事 次の記事
feedback
Top