ウイルス
Online ISSN : 1884-3433
Print ISSN : 0042-6857
ISSN-L : 0042-6857
風疹の研究
1. 1967年に富山県下に流行した風疹の流行像および血清疫学に関する研究
松田 宗之香取 幸治宮原 満恵松浦 久美子久保田 憲太郎
著者情報
ジャーナル フリー

1974 年 24 巻 1 号 p. 8-19

詳細
抄録

An epidemic of rubella occurred in Toyama Prefecture in early spring in 1967. A prefecturewide hospital surveilance indicated that the epidemic was mainly localized in the south-westernpart of the prefecture, with Fukumitsu town as its center, that the peak age of the patients was 6 to 7, and that 18 of 22 patients over 20 years of age were female. Fever, whole body skin eruption, and swelling of the cervical lymph node appeared in 72.1%, 68.9%, and 41.6%, respectively, of the patients. Virological and seroepidemiological studies gave the following results.
1. Six strains of rubella virus were isolated from the throat swab and or blood of 5 patients consisting of 1 primary schoolchild, 3 junior-high-school boys, and 1 adult.
2. In patients with clinical manifestations, HI antibody response to rubella virus was rapid. The titer being 1:512 only 4 days after the onset of the disease.
3. After the epidemic, the antibody level was still very low (between ×8 and ×256) among nursery schoolchildren. It became higher with the advance in age. More than a half of the adults examined showed an intermediate antibody level (between ×8 and ×256).
4. Before the epidemic, 2 distinct patterns were observed in different districts with regard to the antibody level in various age groups. On antibody was detected from 2 age groups, 10 to 11 and 2 to 3.
5. The antibody level in adults after the epidemic was much higher than that before the outbreak.
6. Adults whose family member was infected with rubella virus showed a significantly higher peak in the distribution of antibody titers than those whose family member had not been infected with the virus. This may indicate the possibility that adults possessing a relatively low antibody level may have been reinfected with the virus or at least got a booster response to the virus.

著者関連情報
© 日本ウイルス学会
前の記事 次の記事
feedback
Top