抄録
Some new host-range mutants of T4 bacteriophage were isolated and their serological properties and mutation patterns were described.
Four new host-range mutant strains were isolated from an experiment in which a large amount of T4 wild phages had been inoculated with each of several Shigella strains that are all resistant to T4 wild type. These were designated as T4h(BI), T4h(1106), T4h(BIII) and T4h(KA) respectively, according to the name of Shigella strains on which they had been discovered. They were classified into two groups, A and B, from their host-range patterns.
In experiments of serological neutralization with these mutant phages, polyphasic neutralization such as reported in my previous papers with T1 and T2 phages was also observed, suggesting that these mutant phages have a rather complex antigenic structure in their infectious site too.
A discussion was attempted on the problem of the mechanism of phage infection based on these evidences.
