抄録
The mutagenicities of river water from in the upper of Nagara river which was non-pollution river from judgment by pollution indicator with chemical-analysis were investigated by using XAD-2 resin column concentration method and Ames assay as toxic micropollution indicator with bio-assay. And these mutagenicity were compared with those in the lower areas of Nagara river.
In the upper areas of Nagara river, the mutagenicity was detected a little, which was primarily the direct- and indirect-frameshift types. But their intensities of mutagenicity were low, and did not relate to the developments in the uppers. Therefore, these mutagenic materials might be in nature. However, the mutagenic materials which derived from the polar and indirect-base-pair change mutagens were detected only in winter.
In the lower areas of Nagara river, the mutagenicity showed to be derived from the non-polar, direct- and indirect-frameshift mutagens. These intensities of mutagenicity elevated with the increase of COD and TOC.
