水環境学会誌
Online ISSN : 1881-3690
Print ISSN : 0916-8958
ISSN-L : 0916-8958
原著論文
淀川水系における抗生物質,溶存態DNAの挙動と抗生物質耐性菌の特性
越川 博元滝 さやか井口 彩小幡 倫大田中 宏明
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ジャーナル フリー

2008 年 31 巻 11 号 p. 651-657

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Pharmaceuticals and personal care products (PPCPs) such as antibiotics are widely used daily in hospitals and in the home, and are mainly excreted in urine. Treatments of PPCPs are not always sufficient and this may result in the occurrence of drag-tolerant microorganisms in the environment. In this study, the concentrations of the antibiotics levofloxacin (LVFX) and clarithromycin (CAM), total coliform count, fecal coliform count, dissolved DNA concentration, and TEM gene load in river water and discharges in Yodo River basin were analyzed and calculated. The concentrations of LVFX and CAM in the river, water samples and discharges were lower than the MICs, and E.coli JM109 grew on the LB agar plate with 100 ng · l-1 antibiotics. The dissolved DNA in the discharges was found to be approx. 3.4 times higher than that in the river water samples. Although the TEM gene load decreased, the loads of LVFX and CAM remained at least 40% of their cumulative values. Microorganisms were isolated in the presence of 60 μg · ml-1 ABPC, LVFX, CP, CM and VCM. 90% of the isolates from LVFX formed colonies in 60 μg · ml-1 of ABPC, CP, CM and VCM.
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© 2008 公益社団法人 日本水環境学会
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