We have been reported that the effects on neuroreceptor and metabolic analysis of vanadate for the correlation between neurological disorder and vanadium. This report is of biodistribution studies on the location of ascorbic acid in these animals. A solution of sodium ortovanadate (Na3 VO4, 100ppm) was administered into Wistar rats as a drinking water for 10 months. In serum, liver, spleen, kidney and adrenal, the concentration of ascorbic acid were unchanged. The level of ascorbic acid was decreased in brain only with longterm drinking of vanadate. A reduction of ascorbic acid in each part of brain was different.
