It was reported about the chemical structure of Kynureninase (KYN) and other B6 relating enzyme for example decarboxylases of amino acid metabolism.
1. The amino acid sequence of rat liver KYN and AST (GOT) have similarity in amino acid sequence.
2. And the amino acid sequence of active center in KYN, CGL and CGS have also similar sequence of amino acid.
3. 5-OH-Trp. decarboxylase and DOPA decarboxylase activity decreased in Zn2+ administrated rats.
4. Metabolism of Lys. And Trp. were interrelated through 3-amino adipate aminotransferase.
5. Zn2+ content increased in brain-stem especially in Corpus Striatum using VB6 deficient rats.
6. And finally, histamine synthesis by His. Decarboxylase in diabetic rats were also discussed.
