ショ糖摂取ラットの脂質代謝変動に対する食餌フィチン酸レベルの影響

抄録

Sucrose-fed rats elevate hepatic concentrations of total lipids or triglyceride and hepatic activities of lipogenetic enzymes in comparison with corn starch-fed rats. In general, the elevations that had been caused by sucrose feeding were gradually suppressed by the increasing dietary phytate. Activities of intestinal enzymes in sucrose-fed rats were unaffected by dietary phytate. The curative effect of dietary phytate on fatty liver in rats caused by sucrose feeding may be mediated through the depression of hepatic lipogenesis,but not involving the alteration in the activities of intestinal enzymes. These results also suggest that practical level of dietary phytate may affect hepatic lipid metabolism in animals fed on sucrose.