マグネシウム欠乏における栄養生理学的研究 -特に病理組織学的研究-

抄録

Epidemiologically, it has been suggested that dietary magnesium/calcium imbalance is associated with the risk of heart diseases. In the present study, the effects of magnesium deficiency and/or calcium overintake were investigated in rats. Male Sprague-Dawley rats were divided into 4 groups, and respectively fed basal diet (AIN-76) alone (Group 1), calcium-doubled AIN-76 diet (Group 2), magnesium-deficient AIN-76 diet (Group 3) and magnesium Obtained results thus suggested that dietary magnesium deficiency gives rise to retrogressive changes in some organs such as heart, and concurrent calcium overintake synergistically enhances the myocardial injury due to magnesium deficiency.