Effect of resupplying zinc in zinc-deficient rats

抄録

The effects of oral intake of zinc (Zn) were investigated using rats in a Zn deficient state. A Zn-deficient diet was fed to six-week-old male Sprague-Dawley rats for 60 days. Then, a diet containing 20 mg of Zn per 100 g of food was fed for the next 28 days. Abnormalities such as dermatitis, abnormal serum copper/ zinc (Cu / Zn) ratio, and deformed thyroid improved. However, no germ or sperm cells were observed in the testis. These findings suggest that the effects of resupplying Zn are minimal in tissues affected by rapid cell death due to Zn deficiency.