Glucosylceramide extracted from Tamogitake (Pleurotus cornucopia var. citrinopileatus) is expected to lead to skin improvement effect. Therefore, we have developed at 50 mL beverage containing 0.6 mg glucosylceramide extracted from Tamogitake. It has a final purpose is to clarify the safety and efficacy for human in this developed beverage. As a first step, we were carried out a trial to 33 Japanese women of the 40-60 years old to be troubled with skin roughness by an open trial system.
During 12-week trial period, it was drunk this developed beverage of 50 mL/day to 33 subjects. The subjects were allowed to visit the drinking start day (0 week), 6 weeks and 12 weeks. And, we performed medical examination, laboratory tests and skin checks by instruments to the visited subjects.
As a result, this developed beverage which contained 0.6 mg glucosylceramide was suggested to be safety by 50 mL/day drinking of 12 weeks. In addition, it was also suggested that it might be useful for arranging disturbed epidermal turnover rate.
