A STUDY OF INVESTIGATION OF CADMIUM GENOTOXICITY IN RAT BONE CELLS USING DNA MICROARRAY

Ken-ichi OHBA; Youhei OKAWA; Yuki MATSUMOTO; Yasuhiro NAKAMURA; Hisayoshi OHTA

doi:10.2131/jts.32.107

The Journal of Toxicological Sciences

Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350

Toxicogenomics/proteomics Report

A STUDY OF INVESTIGATION OF CADMIUM GENOTOXICITY IN RAT BONE CELLS USING DNA MICROARRAY

Ken-ichi OHBA, Youhei OKAWA, Yuki MATSUMOTO, Yasuhiro NAKAMURA, Hisayoshi OHTA

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JOURNAL FREE ACCESS

2007 Volume 32 Issue 1 Pages 107-109

DOI https://doi.org/10.2131/jts.32.107

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Abstract

To examine the transcriptional responses of rat bone cells continuously exposed to cadmium, we performed DNA microarray analysis. Cadmium increased levels of expression of 13 genes, including genes for Spp1, and reduced those of 10 genes.

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