The Journal of Toxicological Sciences

The Journal of Toxicological Sciences

The Journal of Toxicological Sciences (J. Toxicol. Sci.) is a scientific journal that publishes research about the mechanisms and significance of the toxicity of substances, such as drugs, food additives, food contaminants and environmental pollutants.

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Published by The Japanese Society of Toxicology

3,054 registered articles
(updated on October 29, 2025)

Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350

1.8
2023 Journal Impact Factor (JIF)

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2025 Volume 50 Issue 10

Dihydropyrazine activates the CAMKK2-AMPK-ULK1 signaling pathway in human hepatoma HepG2 cells Madoka Sawai, Yuu Miyauchi, Hisao Kansui, Shinji Takechi
Expression profiles of purinergic P1 and P2 receptors in cultured bovine aortic endothelial cells, bovine aortic smooth muscle cells, and human vascular endothelial EA.hy926 cells Lihito Ikeuchi, Takato Hara, Kazuki Kitabatake, Fumiaki Uchiumi, Chika Yamamoto, Mitsutoshi Tsukimoto, Tomoya Fujie, Toshiyuki Kaji
Spermidine alleviates sepsis-induced acute kidney injury by suppressing apoptosis and inflammation through modulation of TLR4-mediated signaling Yun Shen, Qinyi Shi, Ting Dai, Yi Cai, Mengting Sheng, Ying Qiu, Ming Yang, Sanhong Hu, Bo Cheng
Successful multimodal treatment of venlafaxine overdose-induced catecholamine-refractory shock: a case report Tomoaki Hayakawa, Akimasa Sanagawa, Kazuki Ohashi, Kazuki Kotoge, Ryohei Matsui, Tetsuya Tamura, Jun Monma-Otaki, Yoko Furukawa-Hibi, Tomonori Hattori

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Most viewed articles (September 2025)

1

Nafamostat mesylate sensitizes ovarian cancer cells to carboplatin by promoting the ZNF24-mediated inhibition of WNT2B

Released on J-STAGE: November 01, 2024 | Volume 49 Issue 11 Pages 467-479

Jiehuan Xu, Jianlin Chen, Dao Wang, Yaojun Li, Ping Lian, Xiaozhu Wu, Rong Yan
2

Prolonged toxicity after massive olanzapine overdose: two cases with confirmatory laboratory data

Released on J-STAGE: August 01, 2008 | Volume 33 Issue 3 Pages 363-365

George H. Tse, Maria H. Warner, W. Stephen Waring
3

Oral exposure to polystyrene nanoplastics induces anxiety-like behavior and cognitive deficit accompanied with alteration of neuroimmune markers in rats

Released on J-STAGE: September 01, 2025 | Volume 50 Issue 9 Pages 507-521

Tin-Tin Win-Shwe, Chaw Kyi-Tha-Thu
4

Non-clinical combination toxicology studies: strategy, examples and future perspective

Released on J-STAGE: July 01, 2020 | Volume 45 Issue 7 Pages 365-371

Aida Sacaan, Satoko Nonaka Hashida, Nasir K. Khan
5

Specificity of transaminase activities in the prediction of drug-induced hepatotoxicity

Released on J-STAGE: September 01, 2020 | Volume 45 Issue 9 Pages 515-537

Akio Kobayashi, Yusuke Suzuki, Shoichiro Sugai

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■■ Impact factor ■■
2023：1.8
2022：2.0
2021：1.792
2020：2.196
2019：1.737
2018：1.732
2017：1.719
2016：1.436
2015：1.224
2014：1.292
2013：1.378
2012：1.380
2011：1.522
2010：1.893

Related journals

Sister Journal ”Fundamental Toxicological Sciences”

Annual Meeting of the Japanese Society of Toxicology

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