The Journal of Toxicological Sciences

The Journal of Toxicological Sciences

The Journal of Toxicological Sciences (J. Toxicol. Sci.) is a scientific journal that publishes research about the mechanisms and significance of the toxicity of substances, such as drugs, food additives, food contaminants and environmental pollutants.

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Published by The Japanese Society of Toxicology

3,015 registered articles
(updated on March 22, 2025)

Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350

1.8
2023 Journal Impact Factor (JIF)

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2025 Volume 50 Issue 3

Per- and polyfluoroalkyl substances: toxicokinetics, exposure and health risks Yukiko Fujii, Kouji H. Harada
Male rat-specific fatty change in liver by DS-1971a: Elevation in phospholipids and adenosine as early responses to the fatty change in male rat-derived primary hepatocytes Kazunori Fujimoto, Hiroyuki Kishino, Jun Hirao, Takanori Maejima, Kazuhiko Mori, Yoshimi Tsuchiya
Prolyl hydroxylase domain enzymes (isoforms 1-3, PHD1-3), but not factor-inhibiting HIF-1 (FIH-1), interact with the IKK complex and attenuate LPS-activated NF-kappa-B Akiyoshi Tamura, Koji Kitayama, Mutsumi Adachi, Kentaro Hashimoto, Ami Oguro, Susumu Imaoka
Prolonged QRS duration in patients with acute poisoning occurs both xenobiotics and with low level of potassium: a single-center retrospective case control study Hironori Katsuki, Tetsuhisa Yamada, Katsuhiko Ayukawa

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Most viewed articles (February 2025)

1

Determination of putrefactive amine and ammonia concentrations around decomposed corpses

Released on J-STAGE: February 01, 2025 | Volume 50 Issue 2 Pages 75-81

Hiroaki Sato, Takahiro Umehara, Satoshi Kimura, Toshiko Tanaka, Sang-Eun Kim
2

Perfluorooctane sulfonate induces hepatotoxicity through promoting inflammation, cell death and autophagy in a rat model

Released on J-STAGE: February 01, 2025 | Volume 50 Issue 2 Pages 45-55

Leilei Tang, Jianjun Zhu, Sheng Zhuge, Jiawen Yu, Guojun Jiang
3

Non-clinical combination toxicology studies: strategy, examples and future perspective

Released on J-STAGE: July 01, 2020 | Volume 45 Issue 7 Pages 365-371

Aida Sacaan, Satoko Nonaka Hashida, Nasir K. Khan
4

Microphysiological systems in early stage drug development: Perspectives on current applications and future impact

Released on J-STAGE: March 01, 2021 | Volume 46 Issue 3 Pages 99-114

Anna K. Kopec, Ryuji Yokokawa, Nasir Khan, Ikuo Horii, James E. Finley, Christine P. Bono, Carol Donovan, Jessica Roy, Julie Harney, Andrew D. Burdick, Bart Jessen, Shuyan Lu, Mark Collinge, Ramin Banan Sadeghian, Mazin Derzi, Lindsay Tomlinson, John E. Burkhardt
5

Specificity of transaminase activities in the prediction of drug-induced hepatotoxicity

Released on J-STAGE: September 01, 2020 | Volume 45 Issue 9 Pages 515-537

Akio Kobayashi, Yusuke Suzuki, Shoichiro Sugai

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■■ Impact factor ■■
2023：1.8
2022：2.0
2021：1.792
2020：2.196
2019：1.737
2018：1.732
2017：1.719
2016：1.436
2015：1.224
2014：1.292
2013：1.378
2012：1.380
2011：1.522
2010：1.893

Related journals

Sister Journal ”Fundamental Toxicological Sciences”

Annual Meeting of the Japanese Society of Toxicology

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