The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350
Letter
MUTAGENICITY OF WATER-SOLUBLE FePt NANOPARTICLES IN AMES TEST
Shinya MAENOSONOToshimasa SUZUKISoichiro SAITA
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JOURNAL FREE ACCESS

2007 Volume 32 Issue 5 Pages 575-579

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Abstract
A mutagenicity test was conducted on water-soluble FePt nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA/pKM101, with and without metabolic activation by S9 mix in the preincubation method. Mutagenicity was weakly positive in the TA100 strain without S9 mix (maximum specific activity was 61.6 revertants/mg), but negative in other cases.
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© 2007 The Japanese Society of Toxicology
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