Mutagenicity of water-soluble ZnO nanoparticles in Ames test

Rie Yoshida; Daisuke Kitamura; Shinya Maenosono

doi:10.2131/jts.34.119

Letter

Mutagenicity of water-soluble ZnO nanoparticles in Ames test

Rie Yoshida, Daisuke Kitamura, Shinya Maenosono

Author information

Keywords: ZnO nanoparticle, Tetramethylammonium hydroxide, Mutagenicity, Toxicity, Ames test, Bacterial reverse mutation test

JOURNAL FREE ACCESS

2009 Volume 34 Issue 1 Pages 119-122

DOI https://doi.org/10.2131/jts.34.119

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Abstract

A mutagenicity test was conducted on water-soluble ZnO nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA⁻, with and without metabolic activation by S9 mix in the preincubation method. Mutagenicity was negative in all strains.

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