The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350
Toxicogenomics/proteomics Report
DNA microarray gene expression analysis of human vascular endothelial cells exposed to arsenite
Yasuyuki FujiwaraAkiko HondaMasahiko Satoh
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2010 Volume 35 Issue 2 Pages 275-278

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Abstract

DNA microarray was used to monitor the transcriptional response of human brain microvascular endothelial cells (HBMEC) and human coronary artery endothelial cells (HCAEC) to sodium arsenite (iAsIII). iAsIII enhanced the expression of 10 and 6 genes, and reduced the expression of 45 and 20 genes in HBMEC and HCAEC, respectively. Among the 64 genes whose expression was changed in some way, HBMEC and HCAEC had 5 up-regulated and 12 down-regulated genes in common.

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© 2010 The Japanese Society of Toxicology
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