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The Journal of Toxicological Sciences
Vol. 35 (2010) No. 6 December P 945-946

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http://doi.org/10.2131/jts.35.945

Toxicogenomics/proteomics Report

To elucidate mechanisms of arsenic toxicity and biological defense mechanisms against arsenic, we searched for genes that, when overexpressed, conferred arsenite resistance on yeast. Employing a Saccharomyces cerevisiae open reading frame (ORF) library, four genes associated with arsenite resistance, FAP7, MIG3, TMA19, and YLR392c, were identified.

Copyright © 2010 The Japanese Society of Toxicology

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