The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350
Toxicogenomics/proteomics Report
Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae
Tsutomu Takahashi, Toomi Yano, JunXuan Zhu, Gi-Wook Hwang, Akira Naganuma
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Keywords: Arsenite, Resistance, Yeast, Fap7, Mig3
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2010 Volume 35 Issue 6 Pages 945-946

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Abstract
To elucidate mechanisms of arsenic toxicity and biological defense mechanisms against arsenic, we searched for genes that, when overexpressed, conferred arsenite resistance on yeast. Employing a Saccharomyces cerevisiae open reading frame (ORF) library, four genes associated with arsenite resistance, FAP7, MIG3, TMA19, and YLR392c, were identified.
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2010 The Japanese Society of Toxicology
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