The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
Toxicogenomics/proteomics Report
Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury
Gi-Wook HwangJin-Yong LeeKatsunori RyokeFujio MatsuyamaJong-Mu KimTsutomu TakahashiAkira Naganuma
Author information
JOURNALS FREE ACCESS

Volume 36 (2011) Issue 3 Pages 389-391

Details
Download PDF (71K) Contact us
Abstract

To elucidate the molecular mechanism involved in methylmercury-induced cerebellar disorder, we performed DNA microarray analysis of the cerebellum of methylmercury-treated mice. The expression levels of 21 genes were elevated 2-fold or higher in response to methylmercury, including many genes encoding proteins involved in inflammatory reactions associated with chemokines. The expression levels of 11 genes were reduced by half or more in response to methylmercury.

Information related to the author
© 2011 The Japanese Society of Toxicology
Previous article Next article

Altmetrics
Recently visited articles
feedback
Top