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The Journal of Toxicological Sciences
Vol. 36 (2011) No. 6 December P 855-857

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http://doi.org/10.2131/jts.36.855

Toxicogenomics/proteomics Report

To elucidate the mechanisms underlying adriamycin resistance, adriamycin resistance-related genes were explored using the budding yeast Saccharomyces cerevisiae as a useful eukaryotic model. The CLN1 and CLN2 genes, encoding G1 cyclin, and the ERG13 gene, encoding 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase, were identified.

Copyright © 2011 The Japanese Society of Toxicology

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