Author's Organization：Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science
Chloropeptide, a hepatotoxic mycotoxin of Penicillium islandicum Sopp, induces gross changes in cell morphology including blebbing and ballooning of the cytoplasmic membrane in the isolated hepatocytes, and this hepatotoxic potential of chloropeptide is abolished by microsomal cytochrome P-450 system.
