Abstract
We have determined the nucleotide sequence of 2.0 kb EcoRI segment from the clone λ FC32 of the genomic chicken fibronectin gene, which is called DNA binding domain. This segment overlapped another clone λ FC36 and contained three exons which were 16, 17 and 18. They were classified as Type Ⅲ repeat as originally shown in bovine plasma fibronectin. The average homologies of these three exons among the chicken, rat and human fibronectins in amino acid level are very high (87-98%) compared with that (79-88%) of the exons in the cell binding domain, indicating that this region is highly conservative during the evolution.