Abstract
Canine histiocytic sarcoma (HS) is a disease associated with hyperferritinemia, and the serum ferritin level is considered a useful tumor marker for HS. We expected the serum ferritin concentration to be related to the biological activity of HS and evaluated the change in serum ferritin levels during the treatment course for three cases of canine HS. The serum ferritin level in all three cases of HS decreased in the early period after chemotherapy, but then increased either immediately prior to or at the time of disease relapse. These results suggest that the serum ferritin concentration is a useful marker for monitoring the clinical course of HS.
