Acute Renal Failure after Ingestion of Grapes in a Dog

Abstract

A 3-year-old male Maltese weighing 2.5 kg presented with a two-day history of vomiting and anuria that had begun five hours after ingesting seedless grapes. On blood examination, severe azotemia, hypercalcemia,hyperphosphatemia, hyperkalemia, and mild elevation of plasma hepatic enzymes were detected. Treatment using diuretics, dopamine, and fluid administration was continued for three days but the dog died with anuria four days after the ingestion. Histopathological examination of the kidney showed severe necrosis and degeneration of the epithelial cells of the proximal tubes. From these clinical and histopathological findings, we concluded that the cause of this poisoning was a grape.