Abstract
A 10-year-old castrated American shorthair cat was presented with a swollen left mandibular region, which by fine needle aspiration (FNA) was initially suspected to be salivary mucocele. Reevaluation of the lesion after three months by FNA revealed atypical lymphoid cells with a background of mucus, raising suspicion of lymphoma. Complete remission was achieved via a six-month COP chemotherapy protocol. Two months after completion of chemotherapy, atypical lymphoid cells were again aspirated from the swollen tissue at the same site. The lesion was resected and submitted for histopathological examination. Lymphoplasmacytic lymphoma was diagnosed based on the typical morphology of neoplastic cells and results of immunohistochemistry. Most neoplastic cells were reactive to MUM1 (marker for plasma cells), while a part of the cell population was positive for CD79a (B lymphocytes), and negative for CD3 (T lymphocytes). Though remission was not achieved by administration of chemotherapeutic agents, the cat maintained quality of life for about six months.
