2015 Volume 68 Issue 7 Pages 441-446
We retrospectively investigated a total of 24 dogs with nasal tumors that were treated with megavoltage radiation therapy from 2009 to 2012 at the Veterinary Medical Center of Osaka Prefecture University. For the radiation therapy, a 4 MV X-ray was used, and the prescribed dose was 35.0-47.2 Gy given in 7-8 measures. The dogs received 5.0-5.9 Gy per measure, 1.9-3.3 times a week. The median overall survival time of all 24 dogs was 260 days. The median survival time of dogs with cribriform plate involvement was significantly shorter than that of dogs with an intact cribriform plate. Clinical signs improved in 15 out of 19 dogs after the treatment, and the side effects of the radiation were mild. These findings indicate that our radiation therapy protocol based on TDF for nasal tumor can result in life prolongation, the amelioration of clinical symptoms, and the reduction of radiation side effects.
