In February 2013, several 65- to 75-day-old pigs exhibited convulsive seizures and astasia, and then died during a 4-day period after being moved to pig-fattening farm A. This occurred on three successive occasions. In September of the same year, at commercial farrow-to-finish pig farm B, ten 50-day-old pigs exhibited similar symptoms and died soon after being moved to a piglet house. Autopsies were performed on these cases at both farms, but no remarkable findings were observed. A pathological examination revealed an infiltration of eosinophils into the cerebral parenchyma and meninges and stratified necrosis in the cerebral cortex. A raw chemical inspection of the serum revealed increased sodium ion density and chloride ion density. These cases were diagnosed as sodium poisoning in pigs. Cases of increased sodium ion density with a significant rise in osmotic pressure were seen, which was associated with an increase in the BUN level. An epidemiology investigation showed poor feed-water quality control in the drinking equipment of both farms, and an insufficient amount of drinking water is considered to have been the cause of the pigs' sodium poisoning. The measurement of osmotic pressure in serum thus appears to be useful when determining the degree of dehydration due to sodium poisoning in pigs.
Although omphalitis and persistent urachus are common umbilical disorders seen in calves, these are difficult to diagnose by physical examination alone. The bladder, urachus, and umbilicus of seven calves with umbilical disorders were examined using ultrasound. Two of three calves with local omphalitis showed pus-like accumulation within their umbilici, which were surgically removed. Three of four calves with persistent urachus also showed abscess-like material within their urachi or umbilici, which were surgically removed. One calf with no evidence of pus accumulation developed dysuria. Surgery revealed remnants of the urachus and umbilical arteries, together with adhesion of the urinary bladder and urethra. Ultrasound was useful for diagnosing umbilical disorders in calves. Imaging of the bladder increased the accuracy of diagnosis and localization of the surgical area, which resulted in the selection of precise treatment.
We retrospectively investigated a total of 24 dogs with nasal tumors that were treated with megavoltage radiation therapy from 2009 to 2012 at the Veterinary Medical Center of Osaka Prefecture University. For the radiation therapy, a 4 MV X-ray was used, and the prescribed dose was 35.0-47.2 Gy given in 7-8 measures. The dogs received 5.0-5.9 Gy per measure, 1.9-3.3 times a week. The median overall survival time of all 24 dogs was 260 days. The median survival time of dogs with cribriform plate involvement was significantly shorter than that of dogs with an intact cribriform plate. Clinical signs improved in 15 out of 19 dogs after the treatment, and the side effects of the radiation were mild.These findings indicate that our radiation therapy protocol based on TDF for nasal tumor can result in life prolongation, the amelioration of clinical symptoms, and the reduction of radiation side effects.