Abstract
A total of 20 dogs underwent conventional open ovariohysterectomy (OO, n=10) and laparoscopic ovariohysterectomy (LO, n=10). The number of leukocytes as well as serum c-reactive protein (CRP) and interleukin‐6 (IL‐6) concentrations were measured at 3 hours, 6 hours, 1 day, 3 days and 5 days postoperatively. Significantly lower serum CRP and IL‐6 concentrations and leukocyte numbers were seen at 1 day postoperatively in the LO group than in the OO group. There was no significant difference in surgical time between the LO and OO group. The result suggested that laparoscopic ovariohysterectomy is less invasive than open surgery.