Retrograde Contrast-Enhanced Computed Tomography Cystourethrography Based on Intravesical Pressure

Abstract

In retrograde urography, an excessive amount of contrast medium can cause iatrogenic bladder rupture, although evaluation is impossible without a sufficient dose. While the actual dose of contrast medium varies significantly based on individual factors, the standard dose is only defined based on body weight. We developed a method of retrograde computed tomography (CT) urography that can evaluate the entire lower urinary tract, from bladder to urethra, with a dose of contrast medium based on intravesical pressure, significantly decreasing the risk of bladder rupture. In the present study, we examined this method using healthy dogs. The results suggested that cystourethrography was appropriately performed with the administration of a contrast medium at an intravesical pressure of 15 mmHg in males and 20 mmHg in females.