A Case of a Holstein Cow with Four Different Tumors

Abstract

In a Holstein cow, we found a case with different tumors in the thyroid, adrenal gland, colon and thoracic wall. Based on histopathological, immunohistochemical and molecular biological findings, the thyroid gland was diagnosed as having C-cell carcinoma, the adrenal gland as having pheochromocytoma, the colon as having a gastrointestinal stromal tumor and the thoracic wall as having B-cell lymphoma. Infiltration of the B cell lymphoma was found in the tumor tissue of the C-cell carcinoma. This case was the first report of four different tumors in a cattle.