Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Studies on the Diagnosis of Canine Filariasis
II. Experiments on Microfilariae-Driving Effects of Chemicals Other than Piperazin Preparations
Isamu OishiSeiji Kume
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1959 Volume 12 Issue 1 Pages 12-15

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Abstract
1. Fourteen chemical and medical agents, including india ink and oxygen, were examined for the presence of microfilariae-driving effects. As a result, pilocarpine hydrochloride, daviol or pyrocatechin sodium disulfonate, filarsen or hydrochloride of dichlorophenarsin, and communin or filtrate of culture of Escherichia coli communior were capable of driving microfilariae.
2. Compared with these four agents with regard to the rate and degree of driving microfilariae and side reaction, supatonin or citrate of 1-diethylcarbamyl-4-methyl piperazin, which was studied by the authors in their previous experiments, was found to the fittest for the purpose of clinical diagnosis of canine filariasis.
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